All the people in this countryside area, can count on Jean-Pierre, the doctor who auscultates them, heals and reassures them day and night, 7 days a week. Now Jean-Pierre is sick, so he sees Natalie, a young doctor, coming from the hospital to assist him. But will she adapt to this new life and be able to replace the man that believed to be irreplaceable.
François Sim considers himself worthless and he may have good reasons for that. Hasn't he lost his job as well as his wife Caroline? Isn't he unable to relate to Lucy, his teenage daughter? Didn't he, when he was eighteen miss out on passion whereas the sexy, gorgeous Luigia opened her arms to him? Hasn't he - he who keeps craving communication - invariably proved a dreadful bore to others...? So, when Sim is unexpectedly offered a job, he takes it, hoping one more time to give a little bit of meaning to his life. Even if his task amounts to driving across France and trying to sell... a "revolutionary biological toothbrush" to reluctant dentists!
When 45 year old widower Erwan discovers by accident that the man who raised him isn't his real dad, he begins a search for his biological father. He soon locates the mischievous, 70 something Joseph, whom his mother knew briefly. Erwan falls not only for his charm, but that of the impetuous Anna, who has ties to them both. The conflicting familial loyalties soon become compounded by the pregnancy of his own daughter Juliette, who defiantly refuses to name the father.